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It works by disrupting the interaction between the FOXO4 protein and p53, a key regulator of cell survival

The biological distinctions between LCINS and smoking-related lung cancers necessitate a unique approach to diagnosis and treatment, with integration of environmental exposures and both germline and somatic genetics to deliver precision oncology strategies for the treatment and prevention of this increasingly important disease

LRRK2 mutations impair depolarization-induced mitophagy through inhibition of mitochondrial accumulation of RAB10

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We guide every patient through informed decision-making and medical screening

Multiple studies suggests that a cytotoxic role and prion-like transfer of -synuclein may contribute to its progressive spread across the brain in PD, assuming a gain-of-function 3,27,28